The Role of Emerging Transporters OCTN1 and LAT1 in Drug Transport and Disease Treatment

Includes a Live Web Event on 10/30/2025 at 6:00 PM (EDT)

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This webinar will feature two presentations to help scientists better understand:

1) The expression of OCTN1 in various cell types of the brain such as microglia, neurons, and neural stem cells
2) The role of OCTN1 in the microglia permeation of ergothioneine and the utility of oral ergothioneine as a potential treatment for Alzheimer’s Disease in mice models 3) The role of LAT1 in transporting drugs across the blood-spinal cord barrier and the potential implications of drug-nutrient interactions in modulating the exposure and efficacy of LAT1 drug substrate, pregabalin

The present webinar also aims to recognize graduate students and postdoctoral fellows from academia who carried out transporter-related research and presented their work in the form of a poster in the 26th North American ISSX and 39th JSSX meeting.

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The Role of Emerging Transporters OCTN1 and LAT1 in Drug Transport and Disease Treatment
10/30/2025 at 6:00 PM (EDT)  |  60 minutes
10/30/2025 at 6:00 PM (EDT)  |  60 minutes This webinar aims to introduce novel research on emerging transporters and their potential involvement in disease modulation and treatment. This includes characterizing the activity of OCTN1 and LAT1 in the brain and spinal cord, the role of these transporters in influencing the efficacious exposure of ergothionine and pregabalin and their therapeutic effect in preclinical mice models of Alzheimer's Disease and cold allodynia, respectively.
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