
Upcoming Webinars
- Contains 3 Component(s) Includes a Live Web Event on 10/03/2023 at 11:00 AM (EDT)
This webinar is intended to increase the awareness of TMDD in small molecules and highlight the importance of recognizing TMDD of small-molecule compounds during clinical development.
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- Contains 3 Component(s) Includes a Live Web Event on 10/17/2023 at 11:00 AM (EDT)
This symposium is intended to provide insights on best practices to address the challenges associated with conducting drug transporter studies with compounds that are unstable, sticky or unstable.
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- Contains 3 Component(s) Includes a Live Web Event on 11/07/2023 at 11:00 AM (EST)
This webinar is intended to discuss a prodrug approach to target tumors. Developing tumor targeting prodrugs is highly challenging. There are not many successful examples in the field. Effective screening strategies are much needed to enable identification of successful prodrug candidates. This is a great example to spark some new ideas in the field. The enzymatic processes for prodrug cleavage are unique and the successful screening strategy is highly educational for scientists in the field.
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Recent Webinars
- Contains 3 Component(s)
This webinar will highlight the challenges and limitations for prediction of in vivo clearance for aldehyde oxidase (AO) substrates in human.
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- Non-member - $49
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- Contains 3 Component(s)
Mechanistic insights gained from this study could be used to assist a medicinal chemistry campaign to design compounds that were less prone to the formation of reactive metabolites.
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- Contains 3 Component(s)
This webinar is intended to educate on emerging knowledge on transporter activity modulation in disease state like liver Cirrhosis/hepatic impairment, and its implications on PK in specific populations.
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- Non-member - $49
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- Contains 3 Component(s)
This webinar will highlight opportunities for research collaboration.
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- Contains 3 Component(s)
This webinar aims to introduce various tools/platforms, the use of primary human hepatocyte spheroids, cryo-electron microscopy, and bioengineered microRNA, in drug transporter research and drug discovery.
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- Contains 3 Component(s)
This webinar will highlight the challenges and limitations for prediction of in vivo clearance for aldehyde oxidase (AO) substrates in human.
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- Non-member - $49
- Member - Free!
- Student - Free!
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- Contains 3 Component(s)
In this webinar, we are going to walk through the main elements of an in vitro DDI investigation study with a focus on changes in this new guidance compared to those previously published by FDA, EMA, and PMDA.
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- Contains 3 Component(s)
This webinar will advance that once free drug is correctly interpreted it can move “projected clinical dose” to a holistic central role in the objectives of drug discovery programs, rather than a checklist of arbitrary multiple objectives.
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- Non-member - $49
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- Contains 3 Component(s)
This webinar aims to highlight current knowledge about albumin-mediated uptake by organic anion transporters expressed in liver and kidney. Special emphasis will be placed on in vitro evidence to support the hypothesis and the complexity confounded by the non-specific binding of the drug-albumin complex. Speakers: Mengyue (Melody) Yin, University of Washington, USA Shawn Pei Feng Tan, University of Manchester, UK Panelists: Aleksandra Galetin, University of Manchester, UK Jash Unadkat , University of Washington, USA Yuichi Sugiyama, Josai International University, Japan
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- Contains 3 Component(s)
This webinar, sponsored by Inotiv, will focus on proximal tubule functions and the important role of drug transporters with mediating renal clearance and toxicity.
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