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Featured Product
- Contains 3 Product(s)
This virtual workshop will bring together scientists from academia, industry, and regulatory agencies to share their research findings, experience, and expert views on endogenous biomarkers for drug transporters, an active research area with rapid advances in recent years.
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- Non-member - $400
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- Student - $125
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Upcoming Webinars
- Contains 3 Component(s) Includes a Live Web Event on 08/13/2024 at 11:00 AM (EDT)
This webinar is intended to update the ISSX community on some new development in peptide derivatization strategy that significantly improve the speed and accuracy of softspot and metabolite identification, which is essential for oral cyclic peptide discovery and development.
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- Non-member - $49
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- Contains 3 Component(s) Includes a Live Web Event on 10/22/2024 at 9:00 AM (EDT)
Abstract coming soon.
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- Contains 3 Component(s) Includes a Live Web Event on 11/12/2024 at 9:00 AM (EST)
In this webinar we will discuss efforts for improving the global underrepresentation of African genetics in science. We will further explore the current landscape and challenges in realizing an African hepatic modeling platform - with a specific focus on the development of hiPSC models that can better recapitulate hepatic function.
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- Contains 3 Component(s) Includes a Live Web Event on 11/19/2024 at 11:00 AM (EST)
This symposium/webinar is intended to educate ADME scientists on MPS technology and its potential to generate clinically translatable data.
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Recent Webinars
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This webinar is intended to provide education and updates of this evolving area to scientists and graduate students.
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- Non-member - $49
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This webinar is intended to share knowledge regarding development of a quantitative assay for siRNA using ddPCR.
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- Non-member - $49
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- Student - Free!
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This webinar aims to introduce the use of various tools to elucidate transporter function and consequently, in vivo exposure to transporter substrates. This includes the use of proteomics to inform an efflux ratio-relative expression factor enabling prediction of fetal exposure across the placenta, a novel metabolomics approach to identify biomarkers of renal OAT1/3 and MRP2/4 and lastly, a case study highlighting the importance of elucidating both the pharmacokinetics and pharmacodynamics of a P-gp substrate in determining its efficacy as CNS drug. The present webinar also aims to recognize graduate students and postdoctoral fellows from academia who carried out transporter-related research and presented their work in the form of a poster in 2023 North American ISSX annual meeting.
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- Non-member - $49
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The ISSX New Investigator Group will present this Fireside Chat with Dr. Eric Chan, an influential scientist in the field. This chat session will be moderated by a member of the group and the discussion will include wide-ranging topics such as current scientific trends, leveraging your network, and thinking strategically about your career in industry, academia, and/or government.
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Selective inhibitors of drug metabolizing enzymes are critical for reaction phenotyping to characterize clearance pathways. New selective inhibitors have been identified to enable more effective understanding of mechanisms involved in metabolism and drug-drug interactions. Learning the characteristics of these new selective inhibitors will allow researchers to apply them readily to characterize new drug candidates.
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This symposium is intended to provide perspectives on the impact that the ICH M12 guideline will have on the in vitro DDI studies required for drug development.
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This webinar is intended to increase the awareness of TMDD in small molecules and highlight the importance of recognizing TMDD of small-molecule compounds during clinical development.
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- Non-member - $49
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- Contains 3 Component(s)
This webinar will highlight the challenges and limitations for prediction of in vivo clearance for aldehyde oxidase (AO) substrates in human.
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- Non-member - $49
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- Contains 3 Component(s) Recorded On: 10/17/2023
This symposium is intended to provide insights on best practices to address the challenges associated with conducting drug transporter studies with compounds that are unstable, sticky or unstable.
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In this webinar, we are going to walk through the main elements of an in vitro DDI investigation study with a focus on changes in this new guidance compared to those previously published by FDA, EMA, and PMDA.
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