This course was developed by the ISSX Modeling and Simulation Focus Group and will be moderated by Maria Posada, Ph.D., Eli Lilly and Company, USA, Oliver Hatley, Ph.D., Certara UK, United Kingdom, and Jaydeep Yadav, Ph.D. Merck, USA. This short course will focus on the fundamentals of modeling and simulation, spanning several modeling disciplines, including PBPK, QSP, PopPK and Biopharmaceutics, (small molecules, peptides, proteins, or new modalities). The course will include the fundamentals for beginners, advancement, and application, as well as case examples.

This short course, featured during the 25th North American ISSX Meeting in September 2023, will focus on challenges and advances of transporter mediated drug disposition and translation from preclinical to human.

This short course, featured at the 25th North American ISSX Meeting in September 2023, is aimed at scientists desiring to gain experience in successful IND submissions that enable first-in-human (FIH) studies with clear line of sight to successful approvals.

This short course, featured during the 25th North American ISSX Meeting in September 2023, is designed to provide the audience with state-of-the-art perspectives on the pharmacokinetics (PK) of protein therapeutics.

This short course, featured during the 25th North American ISSX Meeting in September 2023, covers current best practices and regulatory guidance around in vitro studies assessing inhibition and induction of CYPs and UGTs, the use of the in vitro data to project DDIs using static and PBPK modeling, as well as the use of the data to design clinical DDI studies and inform product labels.

This short course, featured during the 24th North American ISSX Meeting in September 2021, reviews the fundamentals in the translation from preclinical data to FIH dose selection and data needed in support of successful IND application and clinical studies.

This short course, featured during the 24th North American ISSX Meeting in September 2021, reviews PBPK models, including best practices for qualifying and validating models.

This short course, featured during the 24th North American ISSX Meeting in September 2021, reviews topics related to tDDIs.

This Short Course, featured during the 24th North American ISSX Meeting in September 2021, discussed discuss how biotransformation work directly influences drug discovery and development in industry.

This ISSX Summer Short Course aimed to introduce innovative in vitro and in vivo translational approaches and knowledge of transporter clinical probes, endogenous biomarkers, transporter induction, and UGT DDI.