Unmasking the Hidden: A Deep Dive into “MISSED” Metabolites | An ISSX 2025 Short Course
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Co chairs: Kevin Johnson, Inotiv, USA and Shuai Wang, Genentech, USA
- Missing metabolites: what’s the big deal?
Shuai Wang, Genentech, USA
- Metabolic Outliers: When Drug Metabolism Goes Off Script
Valerie Kramlinger, Amgen, USA
- From Inception to Detection: Tracking Thiol Drug Metabolites
Simone Schadt, Roche, Switzerland
- Avoiding Missed Metabolites for Confidence at IND Submission
Matthew Hutzler, Inotiv, USA - Mass Balance Study Design and Strategies For Addressing Unexpected Metabolites
Raman Sharma, Pfizer, USA
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Missing metabolites: what’s the big deal? | Shuai Wang, Genentech, USA
Open to view video.
Open to view video.
This short course delves into the emerging issue of "missed metabolites" in drug development, highlighting challenges, case studies, and advanced techniques to enhance metabolite detection and characterization.
Metabolic Outliers: When Drug Metabolism Goes Off Script | Valerie Kramlinger, Amgen, USA
Open to view video.
Open to view video.
This short course delves into the emerging issue of "missed metabolites" in drug development, highlighting challenges, case studies, and advanced techniques to enhance metabolite detection and characterization.
From Inception to Detection: Tracking Thiol Drug Metabolites | Simone Schadt, Roche, Switzerland
Open to view video.
Open to view video.
This short course delves into the emerging issue of "missed metabolites" in drug development, highlighting challenges, case studies, and advanced techniques to enhance metabolite detection and characterization.
Avoiding Missed Metabolites for Confidence at IND Submission Matthew Hutzler, Inotiv, USA
Open to view video.
Open to view video.
This short course delves into the emerging issue of "missed metabolites" in drug development, highlighting challenges, case studies, and advanced techniques to enhance metabolite detection and characterization.
Mass Balance Study Design and Strategies For Addressing Unexpected Metabolites | Raman Sharma, Pfizer, USA
Open to view video.
Open to view video.
This short course delves into the emerging issue of "missed metabolites" in drug development, highlighting challenges, case studies, and advanced techniques to enhance metabolite detection and characterization.